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  • 產品名稱:IL18BP抗原(重組蛋白)

  • 產品型號:1mg
  • 產品廠商:通蔚生物
  • 產品價格:3580
  • 產品庫存:35
  • 產品文檔:
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詳情介紹:



中文名稱: IL18BP抗原(重組蛋白)

英文名稱: IL18BP Antigen (Recombinant Protein)

儲     存:  冷凍(-20℃)

相關類別: 抗原

概     述
 
Fusion protein corresponding to a region derived from 30-194 amino acids of human IL18BP

技術規(guī)格

Full name:

interleukin 18 binding protein

Synonyms:

IL18BPa

Swissprot:

O95998

Gene Accession:

BC044215

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.






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