中文名稱: TGFBI 抗原(重組蛋白)
英文名稱: TGFBI Antigen (Recombinant Protein)
別 名: transforming growth factor beta induced; CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 502-632 amino acids of human TGFBI
技術(shù)規(guī)格
Full name:
|
transforming growth factor beta induced
|
Synonyms:
|
CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1
|
Swissprot:
|
Q15582
|
Gene Accession:
|
BC004972
|
Purity:
|
>85%, as determined by Coomassie blue stained SDS-PAGE
|
Expression system:
|
Escherichia coli
|
Tags:
|
His tag C-Terminus, GST tag N-Terminus
|
Background:
|
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
|